Triglycerides
· Main storage form of fats within the body.
Raised TG
· Investigate – Fasting Lipid, Urine dip [exc. nephrotic syndrome], glucose, LFT, U&Es, TFT
· Secondary causes – DM, Alcohol, Hypothyroidism, nephrotic syndrome, Steroid, Obesity, COC, B Blocker
Management
· Refer immediately if [>10 in diabetics] or [>20]
· Aim < 1.7 – reduce risk of pancreatitis
· Drug treatment only if > 5.6
· Raised cholesterol & TG
· Simvastatin 40mg OD
· Check 8w fasting lipid
· If TG > 5.6, Omacor 1gm BD, increase to 2gm BD if inadequate effect – Recheck 8w
· If still > 5.6 refer or fibrate [measure CK before & 8w after] or nicotinic acid
· Raised TG only
· Omacor 1gm BD, increase to 2gm BD if inadequate effect – Recheck 8w
· If > 5.6 referral