Triglycerides

Triglycerides

· Main storage form of fats within the body.

Raised TG

· Investigate – Fasting Lipid, Urine dip [exc. nephrotic syndrome], glucose, LFT, U&Es, TFT

· Secondary causes – DM, Alcohol, Hypothyroidism, nephrotic syndrome, Steroid, Obesity, COC, B Blocker

Management

· Refer immediately if [>10 in diabetics] or [>20]

· Aim < 1.7 – reduce risk of pancreatitis

· Drug treatment only if > 5.6

· Raised cholesterol & TG

· Simvastatin 40mg OD

· Check 8w fasting lipid

· If TG > 5.6, Omacor 1gm BD, increase to 2gm BD if inadequate effect – Recheck 8w

· If still > 5.6 refer or fibrate [measure CK before & 8w after] or nicotinic acid

· Raised TG only

· Omacor 1gm BD, increase to 2gm BD if inadequate effect – Recheck 8w

· If > 5.6 referral